Specialist in Blood Bank | SBB Lecture Outline

University Health System and Affiliates School of Blood Bank Technology

Location	Lecture Topic
UTHSC	Immunology Lectures
	Host defenses – an overview Antigens Antibodies I – II Preparation of monoclonal antibodies Clinical applications of monoclonal antibodies Major histocompatibility complex Cellular basis for immunity I – V Immediate hypersensitivity I – II Delayed hypersensitivity I Delayed hypersensitivity II Autoimmunity Immunodeficiency disease Transplantation I and II Tumor immunology
UTHSC	Teaching Skills for Health Professional Educators
	Clinical teaching Instructional media Lecturing Principles of teaching and learning Problem-based learning Small group teaching Student Assessment Clinical teaching in cross-cultural settings
STBTC	Blood & Tissue Donation
	Donor marketing and recruitment Donor selection Routine Emergency Pre-Donation process Immunizations, immigration, travel, HIV, HTLV, vCJD, Chagas Disease, babesiosis Donor physical Donor Collection Allogeneic donors Donation: pre and post donation, arm scrub, donation process Emergency collections Donor Apheresis Apheresis Instruments & Donations Donor Services quality control & quality assurance Donor notification, re-entry and lookback protocols Tissue & Cord Blood Screening, collection, processing, and storage Transport and transplantation
STBTC	Donor Blood Testing
	Hepatitis, CMV and syphilis testing HIV & HTLV I/II testing Chagas and West Nile Virus testing Automated ABO & Antibody Screening
STBTC	Component Preparation
	Red Cell metabolism & Preservation of Liquid Red Cells Preparation of components Red cell components Plasma components & fractionation products Platelets and granulocytes Leukocyte reduced components & irradiated components Donor blood testing, labeling, storage, shipping & records, inventory management Managing resources for the community in normal and critical inventory periods
UHS	Transfusion Therapy – Adverse Reactions to Transfusion
	S-I Transfusion and blood bank history Ethics and medical – legal considerations Blood administration Transfusion therapy – red cell components Transfusion therapy – platelets & GC Transfusion therapy – perinatal transfusion Transfusion therapy – Plasma & Cryo Transfusion therapy – Plasma Derivates Growth Factors & pharmacologic agents Intraoperative blood salvage and massive transfusion Massive transfusion of an individual Massive transfusion of a population following a disaster Preoperative, intraoperative hemodilution, intraoperative & postoperative Transfusion reactions – hemolytic Transfusion reactions – non-hemolytic Transfusion transmitted diseases S-II Autologous blood collection & Directed donation Liver Transplantation Support Bone Marrow Transplant / HPC Cord Blood Transplant Therapeutic Apheresis Adverse Effects of Whole Blood and Apheresis Donation & Patient Procedure Therapeutic Phlebotomy
UHS	Special Transfusion Considerations
	Hemolytic Disease of the Newborn Management of Rh Immune Globulin Prevention of Rh Immunization Prenatal / perinatal testing
STBTC	Current Good Manufacturing Practice (cGMP) – I & II
	S-I Laboratory Safety Routine programs and practices Emergency procedures History/Structure of Regulatory organizations Record Keeping, Organization, Personnel & Training Facilities and Safety, Equipment, Supplier Issues & Validation Standard Operating Procedures, Process Control & Error Management S-II Labeling, Final Inspection, Assessments: Internal and External, Process Improvement & Quality Assurance Tissue/ HPC Regulations Clean Room design and specifications Medical Device Requirements
STBTC	Molecular Biology - I
	Molecular Biology Basics Structure of DNA Application of DNA Technology Nucleic Acid Extraction Nucleic Acid Quantitation Polymerase Chain Reaction
UHS	Molecular Biology - II
	Diagnostic Procedures for Analyzing DNA Probe Production Probe Labels Molecular Beacons Future Prospects of Molecular Assays
UHS	Basic Genetics & Paternity Testing
	Basic Genetics, Patterns of inheritance & pedigree charts Population genetics Paternity testing I – II
STBTC	Blood Groups I
	Blood Group nomenclature & role in transfusion Red Blood Cell membrane ABOH Subgroups of ABO Lewis – secretor – Ii P
UHS	Blood Groups II
	Rh I - II - III
UHS	Blood Groups III - a
	MNSs Kell – Duffy Kidd – Lutheran
STBTC	Blood Groups III - b
	Other Blood Groups High & Low prevalence antigens “HTLA” like antibodies
UHS	Histocompatibility
	HLA Molecules Clinical Histocompatibility Testing Typing: Serological Assays and Molecular HLA Typing Crossmatching: Serology and Flow Cytometry Antibody ID/PRA Analysis Bone Marrow Transplantation Organ Transplantation Platelet & granulocyte antigens and antibodies Refractoriness to platelet therapy Clinical significance of non-red cell antigens in transfusion
UHS	Blood Bank Serology - I
	Antibody detection techniques Compatibility tests Direct antiglobulin tests Resolution of serologic problems – Alloantibodies Resolution of serologic problems – Autoantibodies
STBTC	Blood Bank Serology - II
	Resolution of serologic problems – ABO Polyagglutination Quality control, AABB standards, Reference Laboratory Standards and FDA reagent requirements
UHS	Hematology I & II
	S-I Hematopoiesis & RBC morphology Pediatric hematology Hemoglobin Function & Degradation Hemoglobinopathies Thalassemia Anemias Congenital and Acquired Pathophysiology Detection Treatment S-II Immune Hemolytic Anemias Warm Drug induced Cold Leukemia and lymponomas; myelodysplastic disorder Use of Flow Cytometry
UHS	Coagulation & Hemostasis
	Platelet function and disorders Primary hemostasis Secondary hemostasis I – II Coagulation factors and disorders Disseminated intravascular coagulation
UHS	Statistics/Research – I & II
	S-I General quantitative versus categorical data, p value significance Sensitivity; specificity; prevalence; predictive value Chi-square; Fisher’s exact tables Student’s t test; regression analysis S-II Research Quality control & Control charts Laboratory mathematics Critical review of literature Writing Abstracts, reviewing abstracts
UHS	Effective Supervision and Management - I
	Management of financial resources Basic Accounting, Accounting reports and financial statements The accounting process Cost, volume, profit relationships Budgets and budgeting Inventory management Long term budget decisions Management of Laboratory Operations Standard operating procedures Inspections and accreditation Audits / Assessments Quality Management System Laboratory information system Internal and External role of laboratory in an emergency
STBTC	Effective Supervision and Management - II
	Management of human resources Goals of supervision Planning and work organization How to delegate Job description, recruitment, selection and employment Productivity and morale Employee performance appraisal and discipline Employee counseling Disaster Planning Internal and External role of a blood bank in an emergency